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Metformin is one of the most commonly used drugs in the world and has earned its place as the first medication to prescribe for type 2 diabetes and those with type 1 who have insulin resistance. It is effective, inexpensive and has limited side effects. You can read more about why in this 2013 study. Metformin is in a class of drugs called biguanides. It significantly lowers blood sugar for most people. Studied in human since the 1950s, it has a very strong track record of safety and improved outcomes. Side effects tend to be minimal and temporary, though there is a minority of people who do not tolerate it well. It does not cause weight gain or low blood sugars. Brand Names for Metformin Glucophage Glumetza Glucophage XR Riomet Fortamet Brand Names for Metformin in Combination with Other Drugs Glucovance (glyburide) Metaglip (glipizide) Actoplus Met (pioglitazone) PrandiMet (repaglinide) Avandamet (rosiglitazone) Janumet (sitagliptin) How Does Metformin Work? Me...